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KMID : 0364019970300030330
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Korean Journal of Thoracic and Cardiovascular Surgery
1997 Volume.30 No. 3 p.330 ~ p.335
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Pulmonary Aspergillosis in Cardiac Transplant Patients -The Report of Two Cases-
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박국양
김희정/오미혜/홍석근/정일상/박중원/정도현
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Abstract
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Aspergillus infection is a major cause of mortality in individuals with depressed cell-mediated immunity. Despite therapy with intravenous amphotericin B and oral antifungal agents, high mortality has been reported among heart transplant
recipients. We
experience two cases of pulmonary aspergillosis among 15 heart transplantation cases. Both cases were similar in terms of age, time of diagnosis, and medication. Percutaneous needle aspiration biopsy revealed Aspergillus fumigatus in both cases.
The
first case showed multiple aspergilloma on both lung fields and were treated by IV Amphotericin B and oral itraconazole. After completion of treatment, the lesion completely disappeared and he has been followed up for more than one year in his
good
condition. The second case showed a single nodule on his right lower lung field and were treated by both medication and surgery. The patient recovered well had been doing well until 4th postoperative moths when he developed humoral rejection and
expired.
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